Clean rooms are among the most technically demanding construction projects in commercial building. Every surface, seal, and system must perform to exact specifications to maintain the controlled environment your operations depend on. Nardi Construction brings over 30 years of commercial construction experience to clean room projects, delivering certified environments for pharmaceutical, biotech, healthcare, and advanced manufacturing clients.
Based in Gurnee, Illinois, we serve clients throughout Chicagoland and the tristate area, with project capabilities extending nationwide. Whether you need a single ISO 7 compounding suite or a multi-room ISO 5 production facility, our team manages the full build from design coordination through commissioning.
Our Clean Room Construction Services
ISO-Classified Construction
We build clean rooms to ISO 14644 standards, from ISO 5 (Class 100) through ISO 8 (Class 100,000). Each build is engineered for its specific classification, with air change rates, filtration, and material selections matched to your operational requirements and regulatory obligations.
Wall & Ceiling Systems
Clean room envelopes require seamless, non-shedding surfaces. We install modular wall panel systems, flush-mount ceiling grids, and coved base connections that eliminate particle traps. All joints are sealed to maintain room integrity and support validated cleaning protocols.
Filtration & Air Handling
We integrate HEPA and ULPA filtration systems into ceiling plenums and fan filter units, coordinating with mechanical engineers to achieve the air change rates and laminar flow patterns your classification requires. Pressure monitoring and balancing are part of every build.
Flooring & Finishes
Clean room floors must be seamless, chemical-resistant, and easy to sanitize. We install monolithic epoxy, welded sheet vinyl, and raised-access floor systems depending on your process and equipment needs. All finishes are selected for durability and compliance.
Pressure & Contamination Control
Depending on your application, we configure positive pressure rooms to keep contaminants out or negative pressure rooms to contain hazardous materials. Ante-rooms, air showers, pass-through chambers, and gowning rooms are built to support your contamination control strategy.
Mechanical & Electrical
Lab and production equipment requires dedicated electrical circuits, emergency power connections, and mechanical rough-ins for process gases, purified water, and vacuum systems. We coordinate all MEP work to ensure your equipment is supported from day one.
Compliance & Regulatory Standards
Clean room construction is governed by strict regulatory frameworks that vary by industry and application. Nardi Construction has experience building to FDA, cGMP, USP 797/800, and ISO 14644 standards. We work closely with your quality team, validation engineers, and architects to ensure every material, system, and construction method supports a successful certification outcome.
Our approach emphasizes documentation at every stage—from material submittals and weld certifications to as-built drawings and commissioning reports—so your facility has a clear audit trail from construction through qualification.
Industries We Serve
Our clean room construction experience spans a range of controlled-environment applications, including:
- Pharmaceutical manufacturing and compounding pharmacies
- Biotech research and development labs
- Medical device assembly and packaging
- Semiconductor and electronics manufacturing
- Aerospace and defense production
- Hospital pharmacies and sterile processing
Start Your Clean Room Project
Clean room construction requires early planning and close coordination between the construction team, engineers, and end users. The sooner we're involved in your project, the smoother the process will be. Nardi Construction offers free consultations for clean room projects of all sizes and classifications.